What is dabigatran etexilate?

Dabigatran etexilate is a prescription medication used to slow and inhibit the formation of blood clots.

When do you take dabigatran 110 mg?

Several international regulatory agencies approved 2 doses of dabigatran, 150 mg and 110 mg, for the prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation. The 110 mg dose is recommended in patients at high-risk of bleeding.

What is dabigatran etexilate mesylate used for?

Dabigatran is used to prevent stroke and harmful blood clots (such as in your legs or lungs) if you have a certain type of irregular heartbeat (atrial fibrillation).

What is the cost of dabigatran etexilate?

The cost for Pradaxa oral capsule 75 mg is around $507 for a supply of 60 capsules, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans.

How long can you stay on Pradaxa?

Treatment continues with two 110mg capsules taken once a day for 28 to 35 days after hip replacement and for 10 days after knee replacement. Treatment is delayed in patients who are still bleeding from the site of surgery. A lower dose is used in patients with moderate kidney problems.

How long can you stay on PRADAXA?

What is the most common side effect of PRADAXA?

The most frequent adverse reactions leading to discontinuation of PRADAXA were bleeding and gastrointestinal events (i.e., dyspepsia, nausea, upper abdominal pain, gastrointestinal hemorrhage, and diarrhea).

Which is cheaper eliquis or Xarelto?

NOACs, being relatively new, are only available as expensive brand-name drugs. The average retail price of either Eliquis or Xarelto is around $550 for a monthly supply….How much do these anticoagulants cost?

What is the cheapest blood thinner on the market?

Warfarin (Coumadin, Jantoven) is an inexpensive drug used to treat or prevent clots in the veins, arteries, lungs, or heart. It is more popular than comparable drugs. It is available in multiple generic and brand versions.

What foods should I avoid while taking Pradaxa?

Are There Foods to Avoid While Taking Pradaxa? Patients taking older anticoagulants, such as warfarin, were required to avoid eating foods that were high in vitamin K, such as cabbage, spring onions, broccoli, fermented soy products, Brussels sprouts, and kale and other leafy greens.

What is the safest blood thinner on the market?

Safer Blood-Thinning Drugs to Prevent Stroke The newer medications are Pradaxa (dabigatran), Xarelto (rivaroxaban), Eliquis (apixaban), and most recently Savaysa (edoxaban) — which work by preventing pooled blood in the heart from clotting. Unlike warfarin, the newer drugs are safer and easier for patients to use.

How many mg of dabigatran is in a capsule?

Each capsule contains 110 mg of dabigatran etexilate base (as mesilate salt). Reg. No. 42/8.2/0131 S4 Pradaxa® 150 mg. Each capsule contains 150 mg of dabigatran etexilate base (as mesilate salt).

How big should you be to take dabigatran etexilate?

The International Society on Thrombosis and Haemostasis (ISTH) 2016 guideline suggests avoiding the use of dabigatran etexilate in patients with a BMI >40 kg/m 2 or weight >120 kg due to the lack of clinical data in this population.

What is the molecular weight of dabigatran etexilate mesylate?

The empirical formula is C34H41N7O5 ⋅ CH4O3S and the molecular weight is 723.86 (mesylate salt), 627.75 (free base). The structural formula is: Dabigatran etexilate mesylate is a yellow-white to yellow powder. A saturated solution in pure water has a solubility of 1.8 mg/mL.

Are there any drug interactions with dabigatran etexilate?

Drug Interactions. Cobicistat: May increase serum concentrations of the active metabolite(s) of Dabigatran Etexilate. Monitor therapy Collagenase (Systemic): Anticoagulants may enhance the adverse/toxic effect of Collagenase (Systemic). Specifically, the risk of injection site bruising and/or bleeding may be increased.