What is a tiling screen?

A tile, live tile, and a user tile are all a new feature introduced with Windows 8 and shown on the Windows 8 Start screen. Live tiles are capable of displaying updated information such as weather information, stocks, or other types of notification information.

Why did encode use tiling arrays?

Genomic tiling arrays or next generation sequencing provide a useful alternative for quantifying and characterizing transcription across the genome without requiring prior knowledge of gene or RNA transcript sequences. Tiling arrays are designed to cover the entire genome, selected chromosomes or contigs of the genome.

What is the process of DNA microarray?

The basic principle behind the DNA microarray is “nucleic acid hybridization”. In this process, two complementary strands of a DNA are joined together by hydrogen bonds to form a double-stranded molecule. This helps researchers to compare and analyze the DNA or RNA molecules of identical sequences.

What are the steps in making a microarray slide?

Terms in this set (10)

1. Print DNA sequences onto a slide.
2. Isolate mRNA from normal and “experimental” cells.
3. Prepare labeled cDNA from each of these mRNA samples.
4. Hybridize (bind) labeled cDNAs to the gene sequence printed on the slide.
5. Visualize the results by viewing the different colors on the microarray.

What does tile mean in math?

A tessellation or tiling of a flat surface is the covering of a plane using one or more geometric shapes, called tiles, with no overlaps and no gaps. In mathematics, tessellations can be generalized to higher dimensions and a variety of geometries.

How can you add tiles to your start screen?

To create additional space for more tiles, click on the Start button > Settings > Personalization > Start. On the right pane, select “Show more tiles.” Click on the Start button and you’ll see that the tiled area is larger, creating more space for further tiles.

What is a tile array?

Tiling arrays are a subtype of microarray chips. Like traditional microarrays, they function by hybridizing labeled DNA or RNA target molecules to probes fixed onto a solid surface. Tiling arrays are a useful tool in genome-wide association studies.

What are the 7 steps of DNA microarray?

A basic protocol for a DNA microarray is as follows:

• Isolate and purify mRNA from samples of interest.
• Reverse transcribe and label the mRNA.
• Hybridize the labeled target to the microarray.
• Scan the microarray and quantitate the signal.

What are the uses of DNA microarray?

The DNA microarray is a tool used to determine whether the DNA from a particular individual contains a mutation in genes like BRCA1 and BRCA2. The chip consists of a small glass plate encased in plastic. Some companies manufacture microarrays using methods similar to those used to make computer microchips.

What is tiling Where do we see tiling?

In the most general sense of the word, a tiling is just a way of decomposing some space into lots of little pieces (tiles) that fit together without gaps or overlaps. Land ownership gives a tiling of the surface of the earth! Tilings are literally everywhere.

How are tiling arrays different from traditional microarrays?

Tiling arrays differ from traditional microarrays in the nature of the probes. Instead of probing for sequences of known or predicted genes that may be dispersed throughout the genome, tiling arrays probe intensively for sequences which are known to exist in a contiguous region.

How is a tiling array used in gene expression profiling?

A tiling array is an oligonucleotide-based whole-genome microarray, and has proved to be very useful for whole-genome functional analysis beyond simple gene-expression profiling. Because the tiling array is a variation of the microarray, it is conducted in the same way as a regular expression microarray, the main difference being the probe design.

How are probes used in a tiling array?

Tiling arrays are designed to walk along a section of sequence with each probe representing one of the four nucleotides at a single nucleotide position. Microarray and global gene-expression profiling is a crucial genomic technology. The term microarray is often used synonymously with DNA microarray and high-throughput gene-expression measurement.

How are tiling arrays used to study the genome?

Tiling arrays provide an unbiased tool to investigate protein binding, gene expression and gene structure on a genome-wide scope. They allow a new level of insight in studying the transcriptome and methylome. Drawbacks include the cost of tiling array kits.