Can I take baclofen for sleep?

Baclofen is a gamma-aminobutyric acid receptor agonist used primarily to treat spasticity in various medical conditions. Several studies have noted that baclofen, when used to treat nocturnal gastroesophageal reflux, sleep-related periodic leg movements, and sleep apnea, resulted in an improvement in sleep parameters.

How do you test for baclofen?

Baclofen is usually detectable in urine tests for up to two days, although individuals taking large amounts of the drug may have a longer window of detectability.

How does baclofen work in the brain?

How Baclofen Affects the Brain and Body. Baclofen is classified as a central nervous system depressant, along with being a skeletal muscle relaxant. Its chemical structure is similar to GABA, a neurotransmitter that calms neural activity. When it’s taken, the drug activates GABA receptors in the brain.

What does baclofen bind to?

Chemically, baclofen is a derivative of the neurotransmitter γ-aminobutyric acid (GABA). It is believed to work by activating (or agonizing) GABA receptors, specifically the GABAB receptors. Its beneficial effects in spasticity result from its actions in the brain and spinal cord.

Are there any side effects to taking baclofen?

Along with its needed effects, baclofen may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking baclofen:

Where does baclofen go in the spinal cord?

Baclofen is given intrathecally (directly into the spinal cord) or orally (by mouth).

How do you measure the dose of baclofen?

Shake the oral suspension (liquid) before you measure a dose. Use the dosing syringe provided, or use a medicine dose-measuring device (do no use a kitchen spoon). Call your doctor if your muscle symptoms do not improve, or if they get worse.

Can A baclofen injection be used as an injection?

Patients are usually started on the lowest possible effective dosage in order to reduce the risk of side effects. Baclofen is available as an injection as well, which is administered through an implantable pump. There is a risk of dependence with the use of baclofen.