How does law of Bergonie and Tribondeau affect the radiosensitivity of tissue?

The law of Bergonie and Tribondeau is that the radiosensitivity of a biological tissue is directly proportional to the mitotic activity and inversely proportional to the degree of differentiation of its cells.

Which Tumours are radiosensitive?

Classification of tumor radiosensitivity is based on histology and divided into radiosensitive and radioresistant tumors based on their response to conventionally fractionated radiotherapy. Radiosensitive tumors include: Lymphoma. Myeloma….Radioresistant tumors include:

• Renal cell.
• Melanoma.
• Thyroid.
• Colorectal.

What tissue is most radiosensitive?

Rapidly proliferating non-differentiated cells are the most radiosensitive. Well known representatives of this class of cells are the stem cells of the hematopoietic tissues and the cells of the intestinal crypts. The differentiated fixed postmitotic cells are the most radioresistant.

What are the physical factors that affect radiosensitivity?

Radiosensitivity depends on several factors. These factors include the ability to repair damage, hypoxia, cell cycle position, and growth fraction. In addition, the volume of the initial tumor has been demonstrated to influence the ability to eradicate tumors.

Which part of the body is most sensitive to radiation?

Radiation in high doses can be dangerous no matter what, but some parts of the body are more sensitive than others. The most sensitive parts of the human body are the lymphoid organs, bone marrow, blood, testes, ovaries and intestines, according to the Collaboration for Nondestructive Testing[1].

What is somatic effect of radiation?

Biological Effects of Radiation 91. SOMATIC CELL MUTATIONS AND CANCER. A long-term somatic effect is the damage to cells that are continually reproducing. These cells are the most sensitive to radiation because any changes made in the parent cell’s chromosome structure will be transmitted to its daughters.

What makes a tumor radiosensitive?

Which human organ is highly radiosensitive?

From these discussions we can conclude that Bone marrow is the most radiosensitive tissue of the body.

What types of cells are most sensitive to radiation damage quizlet?

stem cells are more sensitive to radiation than mature cells.

How do you cleanse your body from radiation?

Take a warm shower and gently wash yourself with lots of soap. Do not scald, scrub, or scratch your skin. Your skin helps protect the inside of your body from radioactive material. Wash your hair with shampoo or soap.

What organs are affected by radiation?

Let’s do a head-to-toe walk-through to investigate how high doses of radiation can damage the human body.

• Brain. Nerve cells (neurons) and brain blood vessels can die, leading to seizures.
• Eyes. Radiation exposure increases the risk of cataracts.
• Thyroid.
• Lungs.
• Heart.
• GI tract.
• Reproductive organs.
• Skin.

What is the law of Bergonie and Tribondeau?

The law of bergonie and tribondeau Introduction  In 1906 one of radiology’s most important discoveries was made-the law of Bergonie and Tribondeau. Statement • Stem cells are radiosensitive.  Low metabolic rate decreases radiosensitivity and high metabolic rate increases radiosensitivity.

Why was Tribondeau important to the RST?

Tribondeau was one of the rst histologists who epididymitis. He also became famous because he developed staining techniques for bacteriology. In 1918, he succumbed from u epidemic in Corfu I sland (Hoerni 2007). (Regaud 1982) (Figure 1c). Back to L yon in 1893, he worked mercury. In Renaut ’ s laboratory, Regaud early improved

What did Regaud and Blanc conclude in 1906?

Regaud undertook to repr oduce the experiments of 1906). In their July 1906 paper, Regaud and Blanc concluded: pathological, and particularly on cancer. (Regaud and Bergoni é and Tribondeau (Bergoni é and Tribondeau 1906).