What does Brugia malayi cause?

Brugia malayi is one of the parasitic nematodes that cause lymphatic filariasis which affects 120 million people worldwide.

What is the difference between Brugia malayi and Brugia timori?

The microfilariae of Brugia timori are longer and morphologically distinct from those of Brugia malayi and Wuchereria bancrofti, with a cephalic space length-to-width ratio of about 3:1. B. timori more closely resembles the symptoms caused by B. malayi and morphologically resembles B.

What is the common name of Brugia malayi?

Filarial nematode worm
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Where is Brugia malayi in human body?

During a blood meal, an infected mosquito introduces third-stage filarial larvae onto the skin of the human host, where they penetrate into the bite wound . They develop into adults that commonly reside in the lymphatics .

How do I get rid of filarial worms?

The main goal of treatment of an infected person is to kill the adult worm. Diethylcarbamazine citrate (DEC), which is both microfilaricidal and active against the adult worm, is the drug of choice for lymphatic filariasis. The late phase of chronic disease is not affected by chemotherapy.

How do filarial worms enter the body?

When a mosquito bites a person who has lymphatic filariasis, microscopic worms circulating in the person’s blood enter and infect the mosquito. When the infected mosquito bites another person, the microscopic worms pass from the mosquito through the skin, and travel to the lymph vessels.

What is the infective stage of filarial worm?

There the microfilariae develop into first-stage larvae and subsequently into third-stage infective larvae . The third-stage infective larvae migrate through the hemocoel to the mosquito’s prosbocis and can infect another human when the mosquito takes a blood meal .

How is filariasis diagnosed?

The standard method for diagnosing active infection is the identification of microfilariae in a blood smear by microscopic examination. The microfilariae that cause lymphatic filariasis circulate in the blood at night (called nocturnal periodicity).

What foods to avoid if you have filaria?

Milk and products, fish, jaggery, sweets and contaminated water must be avoided.

What is the best treatment for filaria?

Diethylcarbamazine citrate (DEC), which is both microfilaricidal and active against the adult worm, is the drug of choice for lymphatic filariasis. The late phase of chronic disease is not affected by chemotherapy. Ivermectin is effective against the microfilariae of W.

Which is the most common site of filariasis disease?

Acanthocheilonemiasis is a tropical infectious disease caused by a multicellular parasite (filarial worm [nematode]), called Acanthocheilonema perstans. This parasite is found most commonly in Africa.

What do filarial worms feed on?

Filariasis is a parasitic disease caused by an infection with roundworms of the Filarioidea type. These are spread by blood-feeding insects such as black flies and mosquitoes.

Who is the primary host of Brugia malayi?

Besides B. malayi, the genus also includes B. timori, which is human parasite causing lymphatic filariasis. Other animal species such as B. pahangi and B. patei infecting dogs and cats. Human are the primary host. Leaf monkeys are also definitive hosts and reservoir of sub periodic B. malayi.

Where does Brugia malayi live in the world?

It is endemic in India, Srilanka, Philippines, Southern Thailand, North Veitnam, China, South Korea and Japan. Besides B. malayi, the genus also includes B. timori, which is human parasite causing lymphatic filariasis.

Which is the best treatment for brugia malayi?

Treatment of Brugia malayi Diethylcarbamagine (DEC): is relatively effective in smaller dose. Dose regimen consists of 50 mg on first day; 50 mg three times daily on 2 nd day; 100 mg three times daily on 3 rd day and finally 2 mg/kg/day in three divided doses from 4 th day till 21 st day.

Why are microfilariae of Brugia malayi found at night?

The microfilariae of B. malayi, for the large part, exhibit a phenomenon called nocturnal periodicity, i.e., they appear in larger numbers in the peripheral circulation at night and retreat during the day. Subperiodic or nonperiodic of B. malayi are also found in certain parts of the world. I. Pathology of acute filariasis