What is ivabradine used for?

Ivabradine is used to treat certain adults with heart failure (condition in which the heart is unable to pump enough blood to the other parts of the body) to decrease the risk that their condition will worsen and need to be treated in a hospital.

Does ivabradine increase blood pressure?

In conclusion, heart rate reduction with ivabradine does not increase central aortic blood pressure and is associated with a marked prolongation of diastolic perfusion time and an improvement in myocardial perfusion index.

Is it safe to take ivabradine?

Ivabradine can cause serious heart rhythm problems. Call your doctor at once if you have chest pressure, racing or pounding heartbeats, very slow heartbeats, weakness, tiredness, severe dizziness, or shortness of breath that is worse than usual.

When should I take ivabradine?

Ivabradine is currently licensed for use in patients with symptomatic heart failure with reduced ejection fraction and a heart rate persistently at least 70 beats per minute in spite of otherwise optimal prognostic heart failure pharmacotherapy.

Can ivabradine cause liver damage?

Ivabradine has not been linked to cases of acute hepatitis, liver failure, chronic hepatitis or vanishing bile duct syndrome. There is no evidence that there is cross sensitivity to hepatic injury between ivabradine and other oral antiangina or antiarrhythmic agents.

Can you take ivabradine at night?

Take ivabradine exactly as your doctor tells you to. It is usual to take a dose twice daily, one in the morning and the other in the evening.

How long does ivabradine stay in your system?

Ivabradine is eliminated with a main half-life of 2 hours (70-75% of the AUC) in plasma and an effective half-life of 11 hours. The total clearance is about 400 ml/min and the renal clearance is about 70 ml/min.

Does ivabradine cause hypotension?

Ivabradine has been shown to cause fetal toxicity in animal studies. Postmarketing adverse effects of ivabradine include syncope, hypotension, angioedema, erythema, rash, pruritis vertigo, and diplopia.

Does ivabradine slow heart rate?

Ivabradine slows the heart rate. It does this by inhibiting the electrical current made by the heart’s natural pacemaker.

Does ivabradine affect the liver?

Does ivabradine help anxiety?

We conclude that ivabradine showed no undesirable effects on anxiety, locomotion or learning; in fact, some of these parameters were even improved. For the first time it has been shown that ivabradine is a safe cardiovascular drug regarding its effect on psycho-behavioral manifestations.

Does ivabradine lower BP?

Ivabradine significantly reduced systolic BP at rest.

How are Ivabradine tablets used to treat heart failure?

1 It is used to treat heart failure (weak heart). 2 It is used in certain patients with heart failure to lower the chance of having to go to the hospital for heart failure that gets worse. 3 It may be given to you for other reasons. Talk with the doctor.

Are there any side effects when taking ivabradine?

Some medicines can cause unwanted or dangerous effects when used with ivabradine. Your doctor may need to change your treatment plan if you use any of the following drugs: other heart medicine or blood pressure medication (such as amiodarone, digoxin, diltiazem, or verapamil ).

What’s the maximum dose of ivabradine you can take?

-Maximum dose: 7.5 mg orally twice a day Use: Treatment of stable symptomatic heart failure due to dilated cardiomyopathy (DCM) in pediatric patients 6 months or older who are in sinus rhythm with an elevated heart rate.

What to do when taking ivabradine at night?

Use care when driving and doing other tasks or actions that call for clear eyesight. This includes driving at night. Talk with your doctor. Check blood pressure and heart rate as the doctor has told you. You may need to have your heart checked before starting this medicine (ivabradine tablets) and while taking it. This includes an ECG.