Is band 41 Lyme specific?

What is the significance of band 41 on the IgM and IgG Western blot? It is not Lyme specific and the CDC requires more bands to be present before a diagnosis. However, it is a band for bacteria so what else could cause that to be positive if not Lyme? The 41 kd band is often found on the Western blot.

What kDa 41?

The 41-kDa protein of human herpesvirus 6 specifically binds to viral DNA polymerase and greatly increases DNA synthesis. Virology.

What is normal range for Lyme disease?

Reference Range Normal levels vary depending on the laboratory assay performed, as follows. Borrelia burgdorferi antibody enzyme immunoassay (Lyme index value) : < 0.9 = negative. 0.91-1.09 = equivocal.

Is band 39 Lyme specific?

Some Lyme specialists and scientists believe that there are five very specific bands on the Western blot test that are highly indicative of Lyme disease: band numbers 23, 31, 34, 39 and 93. If any of these bands are positive and the patient is experiencing symptoms of Lyme disease, they may feel treatment is warranted.

How long can you have lymes disease without knowing?

Symptoms. Late Lyme disease usually develops 6-36 months after a person first receives the causal infectious tick bite. The symptoms of late Lyme disease differ from the earlier stages. In North America, joint pain and swelling is very common.

How do I know if my Lyme disease is cured?

As with many infectious diseases, there is no test that can “prove” cure. Tests for Lyme disease detect antibodies produced by the human immune system to fight off the bacteria (Borrelia burgdorferi) that cause Lyme disease. These antibodies can persist long after the infection is gone.

How long does Lyme IgG stay positive?

IgG antibodies are slower to develop, beginning to show 4-6 weeks after exposure and may peak 4-6 months after exposure. While IgM tends to be associated with an active infection, both IgM and IgG can persist in the blood for many years.

What do the Lyme bands mean?

Each of these bands represents an antibody response to a specific protein found on the spirochete. The 41 band indicates an antibody to the flagella 41 kDa protein and is nonspecific. The 31 kDa band represents the OSPA protein and is specific for just a few species of Borrelia, as is the 34 band OSPB, and 23 kDa OSPC.

Does Lyme disease stay in you forever?

If treated, Lyme disease does not last for years. However, for some people, the after-effects of the disease can linger for months and sometimes even years.

Can you fully recover from Lyme disease?

No. Patients treated with antibiotics in the early stages of the infection usually recover rapidly and completely. Most patients who are treated in later stages of the disease also respond well to antibiotics, although some may have suffered long-term damage to the nervous system or joints.

What foods should be avoided with Lyme disease?

The ‘red flag’ foods that feed inflammation and Lyme are gluten, dairy, and sugar. Many of us have experimented with various gluten-free, dairy-free or other diets. Some individuals get positive results, while others continue to struggle with digestive issues.

What is the 31 kDa band for Borrelia?

The 31 kDa band represents the OSPA protein and is specific for just a few species of Borrelia, as is the 34 band OSPB, and 23 kDa OSPC. Some bands are Lyme Specific, some are not. For example, band 41 can represent Lyme spiroch. etes or gum disease spirochetes.

Why do I have a positive 41 kD band?

One reason a positive 41 kd band might emerge is that our mouths contain non-pathogenic spirochetes; it is conceivable that some may seed the blood stream periodically and lead to the positive 41kd immune responses. Two types of antibodies are detected in the Western blot test.

Is the 83 and 94 kDa bands species specific?

21 and 25). The 83 and 94 kDa bands are also thought to be species-specific. Many Lyme disease scientists believe that any patient whose IgG Western blot exhibits bands at, say, any three (or even two) of these locations almost certainly has Lyme disease, regardless of whether or not any other bands are present.

Where to find the 41 kD band on the blot?

Optimal Result: 0 – 0.001 Units. The 41 KD band is often found on the Western blot. A recent study looked at the banding patterns of patients with chronic Lyme disease and healthy controls from the inner city of New York who have never had Lyme disease.