What is the drug Tasigna used to treat?

Nilotinib is used to treat a certain type of blood cancer (chronic myelogenous leukemia-CML). It works by slowing or stopping the growth of cancer cells.

Is Tasigna a form of chemotherapy?

Nilotinib is the generic for the trade chemotherapy drug Tasigna. In some cases, health care professionals may use the trade name Tasigna when referring to the generic drug name nilotinib. Drug Type: Tasigna is targeted therapy.

Can Tasigna cure CML?

Nilotinib (Tasigna) is another second-generation TKI that targets the BCR-ABL protein. This drug can be used as a first treatment for CML, and is also used for people who can’t take imatinib or whose CML no longer responds to it.

Is Tasigna better than Gleevec?

Tasigna® (nilotinib) is superior to Gleevec® (imatinib) for the treatment of patients with Philadelphia chromosome-positive chronic myeloid leukemia (CML), according to the results of two studies presented at the 54th Annual Meeting of the American Society of Hematology in Atlanta, Georgia.

Does Tasigna weaken your immune system?

This medication decreases bone marrow function, an effect that may lead to a low number of blood cells such as red cells, white cells, and platelets. This effect can cause anemia, decrease your body’s ability to fight an infection, or cause easy bruising/bleeding.

Does Tasigna cause heart problems?

Tasigna (nilotinib) side effects range from nausea, diarrhea and headaches to cardiovascular problems and irregular rhythms that may lead to sudden death.

Can I drink alcohol with Tasigna?

However, Tasigna and alcohol can each cause liver problems when used alone. Drinking alcohol while you’re taking Tasigna could further increase your risk of liver damage. Talk with your doctor about whether it’s safe for you to drink alcohol during Tasigna treatment.

Does Tasigna make you tired?

The median actual dose intensity was 593 mg/day in the Tasigna 300 mg twice daily group. The most common (greater than 10%) non-hematologic adverse drug reactions were rash, pruritus, headache, nausea, fatigue, alopecia, myalgia, and upper abdominal pain.

Can you live a long life with CML?

Overall survival rates Cancer survival rates are typically measured in five-year intervals. According to the National Cancer Institute , overall data shows that almost 65.1 percent of those who are diagnosed with CML are still alive five years later.

Does tasigna cause weight gain?

You may have weight loss or weight gain during Tasigna treatment. In clinical studies, between 1% and 10% of people who took Tasigna had changes in their weight. Rapid and unexplained weight gain may be a symptom of edema (fluid retention) in your body. Other symptoms of edema include shortness of breath and swelling.

What are the side effects of taking Gleevec?

Side Effects Upset stomach, nausea/vomiting, diarrhea, headache, muscle/joint pain, muscle cramps, dizziness, blurred vision, or drowsiness may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. People using this medication may have serious side effects.

How much lactose is in Tasigna 150mg capsules?

Qualitative and quantitative composition One hard capsule contains 150 mg nilotinib (as hydrochloride monohydrate). One hard capsule contains 117.08 mg lactose monohydrate. For the full list of excipients, see section 6.1. 3. Pharmaceutical form

When to take Tasigna 200 mg hard capsules?

Tasigna should be taken twice daily approximately 12 hours apart and must not be taken with food. The hard capsules should be swallowed whole with water. No food should be consumed for 2 hours before the dose is taken and no food should be consumed for at least one hour after the dose is taken.

How much Nilotinib is in a Tasigna capsule?

Tasigna (nilotinib) capsules, for oral use, contain 50 mg, 150 mg, or 200 mg nilotinib base, anhydrous (equivalent to 55 mg, 166 mg, and 221 mg nilotinib monohydrochloride monohydrate respectively) with the following inactive ingredients: colloidal silicon dioxide, crospovidone, lactose monohydrate, magnesium stearate and poloxamer 188.

What is the recommended dosage of Tasigna for children?

The recommended dosage of Tasigna for pediatric patients is 230 mg/m 2 orally twice daily, rounded to the nearest 50 mg dose (to a maximum single dose of 400 mg) (see Table 1). If needed, attain the desired dose by combining different strengths of Tasigna capsules.