What is liquid-phase microextraction?

Liquid-phase microextraction is a miniaturized form of traditional liquid–liquid extraction in which the extracting organic phase is limited to a few microliters for extraction of target analytes.

What is hollow fiber liquid-phase microextraction?

Hollow fiber liquid-phase microextraction (HF-LPME) offers an efficient alternative to classical techniques for sample preparation and preconcentration. Features include high selectivity, good enrichment factors, and improved possibilities for automation.

What is dispersive liquid liquid microextraction?

Dispersive liquid-liquid microextraction (DLLME) is an extraction technique developed within the last decade, which involves the dispersion of fine droplets of extraction solvent in an aqueous sample. Dairy products present a complex sample matrix and the removal of interfering matrix components can prove troublesome.

What is single drop microextraction?

Single-drop microextraction (SDME) is often used to represent the acceptor phase where only a small microdroplet (0.5–2.0 µl) is suspended on the tip of a microsyringe; while liquid–liquid microextraction (LLME) is used when the acceptor phase is >10 µl [2].

What does liquid phase microextraction ( LPME ) mean?

Liquid-Phase Microextraction (LPME) is a methodology that was developed by miniaturising Liquid–Liquid Extraction (LLE), greatly reducing the volume of solvent to just a few microlitres.

Are there drawbacks to liquid phase microextraction?

However, conventional sample-preparation techniques [i.e. liquid-liquid extraction (LLE) and solid-phase extraction (SPE)] have involved drawbacks (e.g., complicated, time-consuming procedures, large amounts of sample and organic solvents and difficulty in automation).

How does dispersive liquid microextraction ( dllme ) work?

Dispersive liquid-liquid microextraction (DLLME)  This technique uses μL volume of extraction solvent along with a few mL of dispersive solvents.  A cloudy solution is formed when an appropriate mixture of extraction and dispersive solvents is injected into an aqueous sample containing the analytes of interest.

How is solid phase microextraction used in SPME?

In SPME, micro-quantities of solid sorbent or liquid polymer in an appropriate format are exposed to the sample for a well-defined period of time. Quantification is based on the amount of analyte extracted under the appropriate conditions.