Is arthrogryposis a form of muscular dystrophy?

Arthrogryposis is characterized by multiple joint contractures caused by abnormalities of muscle (muscular dystrophy, congenital myopathies, congenital absence of muscle), abnormal nerve function or innervation (central nervous system malformations, congenital neuropathy, failure of nerves to form or myelinate.

What type of disability is arthrogryposis multiplex congenital?

Arthrogryposis (Arthrogryposis Multiplex Congenita) is a term describing the presence of a muscle disorder that causes multiple joint contractures at birth. A contracture is a limitation in the range of motion of a joint.

Can arthrogryposis be passed on?

Arthrogryposis multiplex congenita (AMC) is not inherited in most cases; however, a genetic cause can be identified in about 30% of affected people.

How common is AMC?

The condition has been reported in individuals of Asian, African and European descent. Isolated congenital contractures affect approximately 1 in 500 individuals in the general population. AMC affects approximately 1 in 3,000 individuals. AMC is, by definition, present at birth (congenital).

Is arthrogryposis progressive?

The management of spinal deformities is similar to that in patients with muscular dystrophy, but with the advantage that arthrogryposis multiplex congenita is not a progressive disease.

What is the prognosis for arthrogryposis?

Prognosis. The lifespan of an individual with arthrogryposis is usually normal but may be altered by heart defects or central nervous system problems. In general, the prognosis for children with amyoplasia is good, though most children require intensive therapy for years.

Does arthrogryposis worsen?

Arthrogryposis does not get worse over time. For most children, treatment can lead to big improvements in how they can move and what they can do. Most children with arthrogryposis have typical thinking and language skills. Most have a normal life span.

Does arthrogryposis cause pain?

A literature review by Cirillo et al indicated that in patients with arthrogryposis, adults have a greater tendency to experience pain than do children, with self reports of pain being more common in individuals in whom multiple corrective procedures have been performed.

How long can you live with arthrogryposis?

The lifespan of an individual with arthrogryposis is usually normal but may be altered by heart defects or central nervous system problems. In general, the prognosis for children with amyoplasia is good, though most children require intensive therapy for years.

How does arthrogryposis multiplex congenita affect the body?

[1] [2] Arthrogryposis multiplex congenita (AMC) refers to the development of multiple joint contractures affecting two or more areas of the body prior to birth. A contracture occurs when a joint becomes permanently fixed in a bent or straightened position, which can impact the function and range of motion of the joint.

When does arthrogryposis affect two different areas of the body?

When arthrogryposis affects two or more different areas of the body, it may be referred to as arthrogryposis multiplex congenita (AMC). The most common form of AMC is amyoplasia. Arthrogryposis and arthrogryposis multiplex congenita are sometimes used interchangeably. The symptoms of AMC are present at birth (congenital).

What are the symptoms of multiplex congenita ( AMC )?

Symptoms Symptoms. Arthrogryposis multiplex congenita (AMC) refers to the development of multiple joint contractures affecting two or more areas of the body prior to birth. A contracture occurs when a joint becomes permanently fixed in a bent or straightened position, which can impact the function and range of motion of the joint.

What are the signs and symptoms of arthrogryposis congenita Nord?

Signs & Symptoms. In most affected individuals, the fingers are flexed and stiff. Although in most reports, the distal joints (i.e., those joints farthest away from the center of the body) are usually more severely affected, the shoulders and hips (which are proximal joints) often have significant contractures.