What is the most common germ cell malignancy of the ovary?

The most common ovarian germ cell tumor is called dysgerminoma.

Are germinomas malignant?

Like other germ-cell tumors, germinomas can undergo malignant transformation.

Is germinoma benign or malignant?

Germinoma. This is a slow-growing germ cell tumor. It is cancer (malignant). The tumor is called dysgerminoma when it grows in the ovaries.

Is germinoma cancer curable?

Germinoma carry a relatively excellent prognosis. It’s very unlikely that the tumor will spread outside the central nervous system. Overall, germinomas are cured in more than 90 percent of cases.

What is the survival rate of germ cell tumor?

The survival and cure rates also depend on several factors, including the stage of the disease. The cure rate for children with a stage I or stage II germ cell tumor is 90%. The cure rate for a stage III tumor is 87%. The cure rate for a stage IV tumor is 82%.

How do you treat germ cell tumors?

Most patients with a cancerous germ cell tumor will need chemotherapy. The drugs that are commonly used for treating germ cell tumors include bleomycin (available as a generic drug), cisplatin (available as a generic drug), etoposide (Etopophos), and ifosfamide (Ifex).

How is Germinoma treated?

Germinoma is typically treated with radiation and in some cases, chemotherapy. Radiation can be curative for a majority of patients, however the long-term effects of this therapy has led to further investigation of treatments that combine chemotherapy with lower volumes and doses of radiation.

What are the signs and symptoms of pineal tumors?

Some of the common signs and symptoms of a pineal tumor may include:

• Headaches (common)
• Nausea and vomiting.
• Vision changes.
• Trouble with eye movements.
• Tiredness.
• Memory problems.
• Balance or coordination problems.

What causes Germinoma?

Germinomas are rare tumors that primarily occur in children and adolescents. These tumors arise from germ cells, which normally become eggs or sperm after migrating to the ovaries or testes during fetal development. Germinomas occur when these germ cells fail to migrate to the proper location and continue dividing.

Can germ cell tumors come back?

How do providers treat benign (noncancerous) ovarian germ cell tumors? Healthcare providers remove benign tumors surgically. Sometimes, they need to remove the ovary (or part of the ovary) when removing the tumor. Benign tumors rarely grow back after providers remove them.

Is Stage 4 germ cell tumor curable?

Can germ cell tumor go away?

Germ cell tumors tend to respond to treatment and many can be cured, even when diagnosed at a late stage.

What are the symptoms of an ovarian germ cell tumor?

The most common ovarian germ cell tumor is called dysgerminoma. Signs of ovarian germ cell tumor are swelling of the abdomen or vaginal bleeding after menopause. Ovarian germ cell tumors can be hard to diagnose (find) early. Often there are no symptoms in the early stages, but tumors may be found during regular gynecologic exams (checkups).

When do you know if you have suprasellar germinoma?

Given the variable rate of tumor progression, the nonspecific early signs of hypothalamic-pituitary dysfunction (DI) as well as the often negative early imaging studies, the diagnosis of suprasellar germinoma is difficult but should always be considered in the presence of so-called ‘idiopathic’ central DI.

Where does a germinoma occur in the ovary?

When it arises in extragonadal sites such as the pineal region, anterior mediastinum and retroperitoneum, it is termed germinoma. It has been designated seminoma when it occurs in the testes and dysgerminoma when it involves the ovary. Germinomas comprise 10% of ovarian tumors in children and 15% of all germ cell tumors.

When does a seminoma occur in the ovary?

It has been designated seminoma when it occurs in the testes and dysgerminoma when it involves the ovary. Germinomas comprise 10% of ovarian tumors in children and 15% of all germ cell tumors. Seminomas are the most common malignancy found in undescended testes.