What is the cost of docetaxel?

Docetaxel is a member of the mitotic inhibitors drug class and is commonly used for Breast Cancer, Breast Cancer – Metastatic, Gastric Cancer, and others….Intravenous Solution.

How effective is docetaxel for prostate cancer?

Docetaxel, when used with or without prednisone, was the first chemotherapy drug proven to help patients live longer with advanced prostate cancer. The average survival was improved by about 2.5 months when compared to mitoxantrone with or without prednisone.

How long does docetaxel extend life?

Docetaxel extended predicted survival by an average of 0.89 years for patients with metastatic disease and 0.78 years for patients without metastatic disease. Docetaxel also extended discounted QALYs by 0.51 years for patients with metastatic disease and by 0.39 years for patients without metastatic disease.

Who makes docetaxel?

Docetaxel is marketed worldwide under the name Taxotere by Sanofi-Aventis as well as Docefrez by Sun Pharma Global and Zytax by Zydus.

Is docetaxel a strong chemo?

Because the active ingredient, docetaxel, is a strong chemotherapy drug, it also has a long list of side effects. Most of them are typical for drugs in this class, such as nausea, vomiting and temporary alopecia (hair loss).

How bad is docetaxel?

Docetaxel may cause severe lack or loss of strength, which can last a few days up to several weeks. Tell your doctor if you unusual tiredness or weakness. This medicine contains alcohol and may cause some people to become drowsy, dizzy, or less alert than they are normally.

How long can you take docetaxel?

Preventing allergic reactions You usually take them for 3 days, starting the day before each treatment. You can take steroids just a few hours before your treatment if you have prostate cancer. Your doctor can tell you how often you should take the steroids.

Which is better docetaxel or paclitaxel?

In conclusion, docetaxel (100 mg/m2 every 3 weeks) demonstrated superior efficacy compared with paclitaxel (175 mg/m2 every 3 weeks), providing significant clinical benefit in terms of survival and time to disease progression, with a numerically higher response rate and manageable toxicities.

How quickly does docetaxel work?

Docetaxel is given after surgery to reduce the risk of breast cancer coming back in the future. It usually starts within a few weeks of your operation. If you are going to have radiotherapy you will usually complete your course of docetaxel first. When chemotherapy is given after surgery it is called adjuvant therapy.

Can you live 10 years with metastatic breast cancer?

What is the prognosis? While there is no cure for metastatic breast cancer, there are treatments that slow the cancer, extending the patient’s life while also improving the quality of life, Henry says. Many patients now live 10 years or more after a metastatic diagnosis.

Does anyone survive metastatic prostate cancer?

Once prostate cancer has spread beyond the prostate, survival rates fall. For men with distant spread (metastasis) of prostate cancer, about one-third will survive for five years after diagnosis.

Is it safe to take docetaxel with prednisone?

Purpose: The TAX 327 study compared docetaxel administered every 3 weeks (D3), weekly docetaxel (D1), and mitoxantrone (M), each with prednisone (P), in 1,006 men with metastatic hormone-resistant prostate cancer (HRPC).

How many mg of Docetaxel can you take per square meter?

For docetaxel, no more than two dose modifications (decreases to 65 mg per square meter and 55 mg per square meter) were allowed.

Is there a limit to hormonal therapy for docetaxel?

Intermittent hormonal therapy was not allowed. For docetaxel, no more than two dose modifications (decreases to 65 mg per square meter and 55 mg per square meter) were allowed.

What are the side effects of docetaxel injections?

Less Common. Bloody nose. body aches or pain. change in the color of the fingernails or toenails. dry, red, hot, or irritated skin at the injection site. headache. hoarseness. loosening or loss of the fingernails or toenails, sometimes painful.