What causes lobular panniculitis?

Lobular panniculitis may also be an expression of infections, trauma, or factitial causes involving the subcutaneous fat. Lipoatrophy refers to a loss of subcutaneous fat due to a previous inflammatory process involving the subcutis, and it may be the late-stage lesion of several types of panniculitis.

What is lobular panniculitis?

Atypical lymphocytic lobular panniculitis (ALLP) is a rare T-cell dyscrasia of the subcutaneous fat. It typically presents with indurated erythematous nodules on the lower extremities and often will have a relapsing and remitting course.

What is septal and lobular panniculitis?

Inflammatory lesions of the subcutaneous fat can be divided into three distinct categories: septal panniculitis, in which the inflammation is confined to the interlobular septa of the subcutis; lobular panniculitis, in which the inflammation involves the entire fat lobule and often the septa as well; and panniculitis …

What is septal panniculitis?

Septal panniculitis is a condition of the subcutaneous fat affecting the layer of adipose tissue that lies between the dermis and underlying fascia, of which there are two forms: acute erythema nodosum and chronic erythema nodosum.

Does panniculitis go away?

Often, panniculitis affects the shins and the calves, then spreads to the thighs and upper body. It usually will clear away within six weeks of forming and leave no scar. If anything, sometimes a slight mark, almost like a bruise, will remain but then fade away.

Can panniculitis be cancerous?

Mesenteric panniculitis is usually benign, meaning the condition itself is not dangerous or cancerous. However, complications can occur. Severe inflammation can cause slowing and blockages in the intestines. This can make other symptoms worse, such as nausea and bloating.

Is panniculitis serious?

Mesenteric panniculitis typically isn’t life-threatening. It may go away on its own, or it could develop into a severe disease. But while the inflammation is there, it can cause pain and other symptoms that interfere with your life. Your doctor can give you medicine to manage this inflammation and control symptoms.

What does panniculitis feel like?

The most notable indicator of panniculitis is tender lumps underneath the skin. You may have just one lump or a cluster of them. They may feel like knots or bumps under the skin, or they may be broader, raised swellings called plaques. Sometimes the swellings drain oily fluid or pus.

How do I get rid of panniculitis?

Panniculitis often resolves without treatment, but certain methods can speed up recovery. The best treatment is to tackle the underlying cause. If there is no known cause, doctors may treat panniculitis by reducing the inflammation, and in some cases, surgically removing the bumps or affected areas of skin.

Is panniculitis an autoimmune disease?

Evidence suggests that mesenteric panniculitis is an autoimmune disorder.

Is panniculitis curable?

What are the signs and symptoms of panniculitis?

Panniculitis is a group of diseases whose hallmark is inflammation of subcutaneous adipose tissue (the fatty layer under the skin – panniculus adiposus ). Symptoms include tender skin nodules, and systemic signs such as weight loss and fatigue . Restated, an inflammatory disorder primarily localized in…

What does idiopathic nodular panniculitis mean in medical terms?

General Discussion. Idiopathic nodular panniculitis is a rare spectrum of skin disorders characterized by single or multiple, tender or painful bumps below the surface of the skin (subcutaneous nodules) that usually lead to inflammation of the subcutaneous layer of fat (panniculitis).

Is there a differential diagnosis for panniculitis?

Related Disorders. Comparisons may be useful for a differential diagnosis: Cytophagic histiocytic panniculitis is a rare disorder affecting the skin and the layers of fatty (adipose) tissue directly under the skin (subcutaneous). The first symptom of this disease is typically the appearance of reddened and tender nodules (lesions) under the skin.

How does mesenteric panniculitis affect the small bowel?

Individuals with mesenteric panniculitis develop inflammation and necrosis of the fatty tissue of the mesentery, especially in the area of the small bowel. The condition progresses to cause chronic inflammation of the mesentery. In some patients, ongoing inflammation can result in scarring (fibrosis) of the mesentery.