What are mesoporous silica nanoparticles used for?

Mesoporous silica nanoparticles They have been widely used to load small molecule chemotherapy drugs, nucleic acids, proteins, and other biological macromolecules, and have been successfully applied to the basic research of tumor multimodal treatment.

How do you make mesoporous silica nanoparticles?

Mesoporous silica nanoparticles (MSNs) have been prepared by sol–gel process, using tetraethyl orthosilicate (TEOS) as alkoxide precursor and cetyltrimethylammonium bromide (CTAB) as surfactant.

What are silica nanoparticles?

Colloidal silica (silicon dioxide) nanoparticles are amorphous materials and are generally spherical in shape. They can be made to have a broad range of sizes and their surface chemistry easily modified to target a variety of applications.

What is silica and its uses?

Silica also is used in grinding and polishing glass and stone; in foundry molds; in the manufacture of glass, ceramics, silicon carbide, ferrosilicon, and silicones; as a refractory material; and as gemstones. Silica gel is often used as a desiccant to remove moisture.

What is the best description of nanoparticles?

A nanoparticle is a small particle that ranges between 1 to 100 nanometres in size. Undetectable by the human eye, nanoparticles can exhibit significantly different physical and chemical properties to their larger material counterparts.

Are silica nanoparticles safe?

It has been mentioned that silica nanoparticles are not toxic up to 100 mg/mL concentration if the size of the particles is 100 nm (Meng et al., 2010).

Where are silica nanoparticles found?

Silicon, or Si, is one of the chemical elements found on Earth’s crust. Its oxide forms are silicate (SiO4) and silica (silicon dioxide, SiO2). Si is often used in industry, while its oxide forms are often utilized for biomedical applications.

What is the main use of silica?

Silica has many industrial applications in abrasives and polishes; in glass manufacturing, fillers and extenders, silica brick manufacturing as a catalyst; in specialty coatings, cleaners ceramics, electronics optics, and refractories; in ferro-silicon manufacturing and rubber.

Where can silica be used?

7 surprising uses of silica gel packets

• Rescue a wet cellphone.
• Maintain razor blades Store all your shaving blades in a jar and put a silicon gel packet in it.
• Prevent your silverware from getting tarnished.
• Keep your coffee jar moist-free.
• Protects your leather shoes from moisture.

What are examples of nanoparticles?

In addition, nanoparticles can be classified as hard (e.g., titania [titanium dioxide], silica [silica dioxide] particles, and fullerenes) or as soft (e.g., liposomes, vesicles, and nanodroplets).

What are the applications of nanoparticles?

Nanoparticles are used increasingly in catalysis to boost chemical reactions. This reduces the quantity of catalytic materials necessary to produce desired results, saving money and reducing pollutants. Two big applications are in petroleum refining and in automotive catalytic converters.

Is nano silica toxic?

The unique physico-chemical properties of nano-sized silica that make them attractive for industry may present potential hazards to human health, including an enhanced ability to penetrate intracellular targets in the lung and systemic circulation.

How are mesoporous silica nanoparticles used in biomedical applications?

In the past decade, mesoporous silica nanoparticles (MSNs) have attracted more and more attention for their potential biomedical applications. With their tailored mesoporous structure and high surface area, MSNs as drug delivery systems (DDSs) show significant advantages over traditional drug nanoca …

Who are the authors of mesoporous nanoparticles and drug delivery?

Mesoporous silica nanoparticles: synthesis, biocompatibility and drug delivery Adv Mater. 2012 Mar 22;24(12):1504-34.doi: 10.1002/adma

How are silica nanoparticles used in drug delivery?

Sustained drug release using unmodified silica can be achieved by regulating the pore structure, pore diameter and particle size of the carrier. With modified silica materials conjugated to organosilanes,38 the interaction between the drug molecules and the functional groups delays drug dissolution from MSNs and enables a more sustained release.

How are mesoporous silica materials used in sddss?

Conventional mesoporous silica materials, such as MCM-type materials and SBA-type materials, are utilized as SDDSs by controlling their physical and textural properties. As discussed for the IDDSs, pore morphology and size significantly influence the release rate.