What drug is similar to indomethacin?

Indomethacin is a nonsteroidal anti-inflammatory drug (NSAID) that reduces fever, pain and inflammation. It is similar to ibuprofen (Motrin) and naproxen (Naprosyn, Aleve). Indomethacin works by reducing the production of prostaglandins.

What is the chemical structure of indomethacin?

C19H16ClNO4
Indomethacin/Formula

What does the chemical indomethacin do?

Indometacin is an NSAID with analgesic and antipyretic properties that exerts its pharmacological effects by inhibiting the synthesis of factors involved in pain, fever, and inflammation.

What is the functional group of indomethacin?

Another example of a drug compound with potential conflict between the hydrogen-bonding groups is Indomethacin (see chemical structure below), a non-steroidal anti-inflammatory drug with four functional groups of interest; carboxylic acid, carboxamide, methoxy and chlorophenyl groups.

Is indomethacin more powerful than ibuprofen?

Indocin (indomethacin) works well for mild to moderate pain and swelling, but it shouldn’t be used long-term since it has some serious side effects. Advil (ibuprofen) is effective for treating fever, pain, and inflammation.

Is indomethacin a safe drug?

Indomethacin can increase your risk of fatal heart attack or stroke, even if you don’t have any risk factors. Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG). Indomethacin may also cause stomach or intestinal bleeding, which can be fatal.

Is indomethacin a good painkiller?

Indomethacin is used to relieve pain, swelling, and joint stiffness caused by arthritis, gout, bursitis, and tendonitis. It is also used to relieve pain from various other conditions. This medication is known as a nonsteroidal anti-inflammatory drug (NSAID).

Is indomethacin stronger than ibuprofen?

What is another name for indomethacin?

What Is Indocin? Indocin (indomethacin) and Indocin IV (indomethacin) for Injection is a nonsteroidal anti-inflammatory drug (NSAID) used to treat severe rheumatoid arthritis, ankylosing spondylitis, osteoarthritis, acute gouty arthritis, bursitis, and tendinitis.

Is it OK to take indomethacin and ibuprofen?

Using ibuprofen together with indomethacin is generally not recommended. Combining these medications may increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and rarely, perforation.

Can you drink coffee with indomethacin?

If you have persistent stomach upset, vomit blood or what looks like coffee grounds, or have black, tarry stools, contact your health care provider immediately. It is best to limit or avoid alcohol containing drinks while taking this drug, even with short term use.

How bad is indomethacin?

Serious side effects of Indocin may include heart attack, stroke, skin changes (paleness, blisters, rash, and hives), weight gain, swelling, shortness of breath, tachycardia, unusual bleeding (including GI bleeding), jaundice, stomach pain, and pain with urination, bloody urine, blurry vision, and back pain.

Which is the best description of the pharmacology of indomethacin?

Methods/results: The present article summarizes pharmacologic properties of indomethacin, including pharmacokinetics with particular attention to its distribution into the central nervous system, adverse effects, drug interactions, and mechanisms of action.

What kind of liver disease does indomethacin cause?

Indomethacin has been associated with rare cases of idiosyncratic drug induced liver disease. Indometacin, or indomethacin, is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic properties.

How does indometacin work as an anti inflammatory?

Indometacin, also known as indomethacin, is a nonsteroidal anti-inflammatory drug (NSAID) commonly used as a prescription medication to reduce fever, pain, stiffness, and swelling from inflammation. It works by inhibiting the production of prostaglandin s, endogenous signaling molecule s known to cause these symptoms.

Are there any other drugs similar to indomethacin?

They may contain ingredients similar to indomethacin (such as aspirin, ibuprofen, ketoprofen, or naproxen ).