How fast can you run gentamicin IV?

Gentamicin when given intravenously should be injected directly into a vein or into the drip set tubing over no less than three minutes. If administered by infusion, this should be over no longer than 20 minutes and in no greater volume of fluid than 100 ml.

How do you mix gentamicin IV?

For IV administration, the prescribed dose of gentamicin may be diluted in 100-200mL of sterile normal saline or 5% glucose in water. The concentration of gentamicin in the solution should not exceed 1mg/mL. Infusion periods of 30 minutes to 2 hours have been advocated.

How do you calculate gentamicin?

The dose is calculated using these assumptions:

1. CrCl > 40ml/min at 5mg/kg dose to a maximum of 500mg.
2. CrCl 10-40ml/min at 3mg/kg dose to a maximum of 300mg.
3. CrCl <10ml/min at 1mg/kg dose to a maximum of 120mg.
4. Round the dose up or down to the nearest 20mg increment for doses less than 200mg and 40mg above this.

How often is IV gentamicin given?

The FDA-approved dosage is 3 mg/kg/day IV or IM divided every 8 hours for severe infections and 5 mg/kg/day IV or IM divided every 8 hours for life-threatening infections.

How much gentamicin is in a 100 ml vial?

GENTAMAX® 100 (Gentamicin Sulfate Solution), 100 mg per mL for intrauterine use, is available in 100 mL and 250 mL multiple dose vials. Store between 2oand 30oC (36oand 86oF). REFERENCES 1. Hennessey, PW, et al. In vitroactivity of gentamicin against bacteria isolated from domestic animals.

How often can you take gentamicin in a day?

Susceptible Infections 1 Initial: 4-7 mg/kg/dose IV once/day. 2 Base dose on lean body weight. 3 Subsequent doses: Consult pharmacist.

How much Gentamicin should I take at the end of dialysis?

-Adults: 1 to 1.7 mg/kg IM or IV at the end of each dialysis period. -Children: 2 to 2.5 mg/kg IM or IV at the end of each dialysis period. Peritoneal dialysis: Data not available. Comment: The dose depends on the severity of the infection.

Which is the highest dose of gentamicin or tobramycin?

You may select a specific nomogram by clicking the “Config” icon in the top, right-hand corner of this webpage. The Hartford nomogram was one of the first published extended-interval nomograms. Unlike other nomograms, it uses the highest dose of gentamicin/tobramycin (7 mg/kg versus 5 mg/kg), which achieves a 40% higher peak.