What does a positive extractable nuclear antibody mean?

A positive test result means that the person has more of that autoantibody in their blood than the designated reference value. Autoantibody Test. Results That Support an Autoimmune Disorder Diagnosis.

What does a positive Smith antibody mean?

A positive result for anti-Sm antibodies is consistent with a diagnosis of lupus erythematosus.

What is a Smith AB blood test?

Smith antibody is an antinuclear antibody associated with lupus.

What is Smith IgG?

Sm (SMITH) ANTIBODY IgG It is a component of extractable nuclear antigens also seen in other connective tissue disorders. This assay is useful for evaluating patients with signs and symptoms of a connective tissue disorder in whom ANA is positive.

How does a Smith extractable nuclear antibody test work?

Following is the specimen collection process for Smith Extractable Nuclear Antibody Blood Test: Sample required: Blood Process of obtaining blood sample in adults: A band is wrapped around the arm, 3-4 inches above the collection site (superficial vein that lies within the elbow pit)

What kind of blood test is Smith extractable?

Smith Extractable Nuclear Antibody Blood Test. The Smith Extractable Nuclear Antibody Blood Test helps detect anti-Sm antibodies in cells. It is used to diagnose systemic lupus erythematosus (or lupus).

What makes an extractable nuclear antigen panel extractable?

Extractable Nuclear Antigen Antibodies (ENA) Panel. An extractable nuclear antigen (ENA) panel detects the presence of autoantibodies in the blood that react with proteins in the cell nucleus. These proteins are known as “extractable” because they can be removed from cell nuclei using saline and represent six main proteins (Ro, La, Sm, RNP,…

Which is better anti Smith or anti dsDNA?

Anti Smith Antibody Test. it can also be useful in confirming a diagnosis of systemic lupus. Contrasting anti-dsDNA, anti-Sm does not associate with the presence of kidney lupus. They are connected with central nervous system involvement, kidney disease, lung fibrosis and pericarditis in SLE, but they are not related with disease activity.