When do you use CKD-EPI vs Mdrd?
When do you use CKD-EPI vs Mdrd?
First, we observed that the CKD-EPI equation is a better predictor of risk than the MDRD Study equation in CKD cohorts as well as in cohorts with higher estimated GFR. Improved or similar performance across the range of estimated GFR is important for clinical implementation.
When do you use CKD-EPI formula?
A laboratory that reports eGFR numeric values > 60 mL/min/1.73 m2 should use the CKD-EPI equation, because the CKD-EPI equation is more accurate for values > 60 mL/min/1.73 m2 than is the MDRD Study equation.
What does CKD-EPI mean?
The Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation provides a better definition of cardiovascular burden associated with CKD than the Modification of Diet in Renal Disease (MDRD) Study formula in subjects with type 2 diabetes. Atherosclerosis.
How is CKD-EPI calculated?
The CKD-EPI equation, expressed as a single equation, is: GFR = 141 * min(Scr/κ,1)α * max(Scr/κ, 1)-1
Which is the best cystatin for CKD-EPI?
CKD-EPI Cystatin C is preferred in cirrhotics and other patients with low muscle mass. CKD-EPI Creatinine can be used in settings where cystatin C is not available.
What is the sensitivity of the CKD-EPI equation?
GFR (ml/min/1.73 m2) The sensitivity and specificity of estimated GFR <60 ml/min/1.73 m 2 were 91% and 87%, respectively, using the CKD-EPI equation and 95% and 82%, respectively, using the MDRD Equation. Levey AS, Stevens LA, Schmid CH, et al. A new equation to estimate glomerular filtration rate. Ann Intern Med.
How to calculate the GFR value for CKD-EPI?
BSA (m2) = (W0.425x H0.725) x 0.007184 Unadjusted CKD-EPI eGFR (ml/min) = eGFR (ml/min/1.73 m2) x BSA (m2) / 1.73 BSA = UNADJUSTED GFR GFR VALUE CKD-EPI CREATININE EQ (2009) CKD-EPI CYSTATIN C EQUATION (2012) CKD-EPI CR-CYSTATIN C EQ (2012) MDRD STUDY EQUATION ADDITIONAL INFORMATION Pediatric Calculator MDRD STUDY EQUATION SI Default
What is the MDRD Study equation for cystatin C?
(With SI Units) 4 variable MDRD Study Equation, CKD-EPI Creatinine Equation (2009), CKD-EPI Cystatin C Equation (2012) and CKD-EPI Creatinine-Cystatin C Equation (2012) (with SI Units) using standardized serum creatinine, age, race, gender and serum cystatin C programmed by Stephen Z. Fadem, M.D., FACP, FASN and Brian Rosenthal