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How do you treat an allergic reaction to local anesthesia?

How do you treat an allergic reaction to local anesthesia?

Infrequently, local anesthetics may provoke an allergic or hematologic reaction. Allergic reactions can be treated with diphenhydramine and corticosteroids. Anaphylaxis may also require epinephrine administration. Methemoglobinemia should initially be treated symptomatically.

What can you use if allergic to lidocaine?

Anesthetics that belong in the ester group can be used if patients know they are allergic to lidocaine or another amide medication. If they are unsure, using diphenhydramine can provide adequate relief as well.

Can someone be allergic to local anesthetics?

Allergic reactions to local anesthetics are often attributed to additives such as metabisulfite or methylparaben. True allergic reactions to amide local anesthetics are extremely rare but have been documented.

Which local anesthetics cause allergic reactions?

Ester local anesthetics are associated with a higher incidence of allergic reactions due to one of their metabolites, para-amino benzoic acid (PABA). PABA is structurally similar to methylparaben.

How are local anesthetics related to allergic reactions?

Data synthesis: Local anesthetics are classified as either ester or amide compounds. Esters are associated with a higher incidence of allergic reactions, due to a p-aminobenzoic acid (PABA) metabolite. Amide agents do not undergo such metabolism.

How is systemic toxicity of local anesthetic treated?

Often lethal, local anesthetic systemic toxicity (LAST) was treated with caffeine, ammonia, or even hypodermic ether. The development of procaine in 1904 did not solve the problem of systemic toxicity, and the Committee for the Study of Toxic Effects of Local Anesthetics published a report of 43 fatal cases linked to the use of LAs.

Are there any hypersensitivity to amide local anesthetics?

Amide local anesthetics do not undergo metabolism to PABA, and therefore hypersensitivity to amide local anesthetics is rare. Because of these possible hypersensitivity reactions, many manufacturers have reformulated some of their products to eliminate methylparaben.

What to do in case of local anesthetic emergency?

Management of Local Anesthetic Emergencies: The first consideration is prevention, best accomplished by careful and constant monitoring of cardiovascular and respiratory vital signs and the patient’s state of consciousness after each local anesthetic injection. At the first sign of change, oxygen should be administered.

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