Can lamotrigine cause akathisia?

The combination of aripiprazole, the antipsychotic most associated with akathisia, with lamotrigine and antidepressants may have increased the risk of akathisia, thus resulting in the clinical conditions observed in these two cases.

What neurotransmitters are affected by lamotrigine?

Lamotrigine does not exhibit a high affinity in binding to the following neurotransmitter receptors: adenosine A1 and A2; adrenergic α1, α2, and β; dopamine D1 and D2; γ-aminobutyric acid (GABA) A and B; histamine H1; kappa opioid; muscarinic acetylcholine; and serotonin 5-HT2 (Leach et al., 1991).

What should I avoid while taking lamotrigine?

What Should I Avoid While Taking Lamotrigine? Avoid drinking alcohol or using illegal drugs while you are taking lamotrigine. They may decrease the benefits (e.g., worsen your condition) and increase adverse effects (e.g., sedation) of the medication.

Can lamotrigine cause mental health problems?

Lamotrigine is generally well tolerated; however, some psychiatric problems have been reported in patients using the drug to treat mental disorders (mainly bipolar) or epilepsy. The clinical features of these psychiatric side effects are: affective switches, full acute psychotic episodes, and hallucinations.

Who are the actors in the movie lamotrigine?

Tricia Y Ting 1 , Wenlei Jiang 2 , Robert Lionberger 2 , Jessica Wong 3 , Jace W Jones 3 , Maureen A Kane 3 , Allan Krumholz 1 , Robert Temple 2 , James E Polli 3 Affiliations

Are there any adverse events with generic lamotrigine?

Bioequivalence results in “generic-brittle” patients with epilepsy under clinical conditions support the soundness of the FDA bioequivalence standards. Adverse events on generic were not related to the small, allowable PK differences between generic and brand.

When to adjust lamotrigine dosage for mixed episodes?

-If drugs that induce or inhibit glucuronidation are discontinued, gradually (over a 2-week period) adjust maintenance dose to the target dose of 200 mg/day. -Treatment of acute manic or mixed episodes is not recommended; effectiveness of this drug in the acute treatment of mood episodes has not been established.

What are the affiliations of lamotrigine and Lamictal?

Affiliations 1Department of Neurology, University of Maryland, Baltimore, Maryland, U.S.A. 2Food and Drug Administration, White Oak, Maryland, U.S.A. 3Department of Pharmaceutical Sciences, University of Maryland, Baltimore, Maryland, U.S.A. PMID: 26201987 DOI: 10.1111/epi.13095 Abstract