What is the LD50 of methanol?
What is the LD50 of methanol?
Methanol
| Names | |
|---|---|
| LD50 (median dose) | 5628 mg/kg (rat, oral) 7300 mg/kg (mouse, oral) 12880 mg/kg (rat, oral) 14200 mg/kg (rabbit, oral) |
| LC50 (median concentration) | 64,000 ppm (rat, 4 h) |
| LCLo (lowest published) | 33,082 ppm (cat, 6 h) 37,594 ppm (mouse, 2 h) |
| NIOSH (US health exposure limits): |
How much methanol is lethal?
A potentially lethal dose of methanol is approximately 30 to 240 mL or 1 gram per kilogram. Permanent visual damage may occur with minimum ingestion of 30 mL of methanol. The parent compound, methanol, accounts for the increased osmolality.
How much methanol is lethal through skin?
The lethal dose of pure methanol in humans is estimated at 15.8–474 g/person as the range and 56.2 g/person as the median.
What is a safe level of methanol?
According to the FDA, as much as 500 milligrams per day of methanol is safe in an adult’s diet. In the body, methanol is metabolized in the liver, converted first to formaldehyde, and then to formate. As a building block for many biological molecules, formate is essential for survival.
What is the MSD number for methanol 4 / 20?
MSDS Number: 100000002748 4 / 20 Methanol Molecular formula : C-H4-O Synonyms : Methyl alcohol, SECTION 4. FIRST AID MEASURES General advice : Move out of dangerous area. Consult a physician. Show this safety data sheet to the doctor in atten- dance. Do not leave the victim unattended. Consult a physician.
When did methanol version 2.6 revision date?
Safety Data Sheet Methanol Version 2.6 Revision Date: 08/30/2018 SDS Number: 100000002748 8 / 12 Methanol 67-56-1: Acute oral toxicity : LDLo (Humans): 143 mg/kg Assessment: The component/mixture is toxic after single in- gestion. Acute inhalation toxicity : Assessment: The component/mixture is toxic after short term inhalation.
Are there any cases of methanol resistance in humans?
Folinic acid or folic acid is also administered to enhance the metabolism of formate. There are cases of methanol resistance, such as that of Mike Malloy, whom someone tried and failed to poison by methanol in the early 1930s.
What do you need to know about methanol labchem?
02/18/2020 EN (English US) 2/10 P264 – Wash exposed skin thoroughly after handling. P270 – Do not eat, drink or smoke when using this product. P271 – Use only outdoors or in a well-ventilated area. P280 – Wear protective gloves, protective clothing, eye protection, face protection.