What is a translocation in genetics?

Listen to pronunciation. (TRANZ-loh-KAY-shun) A type of chromosomal abnormality in which a chromosome breaks and a portion of it reattaches to a different chromosomal location.

What is an example of translocation?

The translocation in this example is between chromosomes 14 and 21. When a baby is born with this type of translocation chromosome in addition to one normal 14 and two normal 21 chromosomes, the baby will have Down syndrome. This is also called translocation Down syndrome.

What happens in gene translocation?

A translocation is a chromosomal abnormality whereby there’s a break in the chromosome, one particular chromosome, and that chromosome will then fuse to a different chromosome. And then you have what we call a fusion product.

What causes genetic translocation?

Translocation Down syndrome is a type of Down syndrome that is caused when one chromosome breaks off and attaches to another chromosome. In this case, there are three 21 chromosomes but one of the 21 chromosomes is attached to another chromosome.

What does translocation, genetic mean?

Translocation, Genetic A type of chromosome aberration characterized by CHROMOSOME BREAKAGE and transfer of the broken-off portion to another location, often to a different chromosome. How to pronounce translocation, genetic?

What does translocation mutation cause?

Translocation mutations cause cancers such as leukaemia, infertility and XX male syndrome, etc. Infertility occurs when one of the parents carries a balanced translocation resulting in non-viable fetus even though the parent conceives. XX male syndrome occurs due to the translocation of the SRY gene of the Y chromosome to X chromosome .

What is significance of translocation?

Because translocation is responsible for the delivery of nutrients to developing seeds and fruits , this process is critical to the achievement of optimal crop yield. It also accounts for the ultimate nutritional composition of plant foods important to humans.

What is meant by translocation in biology?

translocation. In genetics, the movement of a portion of one chromosome to another; in protein synthesis, the transfer of the newly elongated peptidyl-tRNA from the amino acyl site to the peptide site of a ribosome; in cell biology, the movement of a molecule across a barrier or between cytosol and membrane surface.