What is a transmucosal?

Medical Definition of transmucosal : relating to, being, or supplying a medication that enters through or across a mucous membrane (as of the mouth) transmucosal fentanyl Noven Pharmaceuticals develops transdermal and transmucosal drug delivery systems and technologies. —

What is mucosal absorption?

Oral mucosal absorption as a sequence of rate processes. The mucosal membranes can act as a storage compartment for drug, extracting drug from the oral cavity until either the distribution equilibrium has been reached.

What is transmucosal drug delivery?

Oral transmucosal delivery refers to the systemic delivery of drug through the mucous membrane of the oral cavity. Different oral transmucosal dosage forms are available for the management of breakthrough pain, such as tablet, lozenge and oral film.

What is the difference between buccal and sublingual absorption?

Sublingual administration involves placing a drug under the tongue and buccal administration involves placing a drug between the gums and cheek.

Why is oral transmucosal absorption a rapid process?

Oral transmucosal absorption is generally rapid because of the rich vascular supply to the mucosa and the lack of a stratum corneum epidermidis. This minimal barrier to drug transport results in a rapid rise in blood concentrations.

What is the medical definition of transmucosal medicine?

Medical Definition of transmucosal. : relating to, being, or supplying a medication that enters through or across a mucous membrane (as of the mouth) transmucosal fentanyl Noven Pharmaceuticals develops transdermal and transmucosal drug delivery systems and technologies. — The Miami Herald, 13 Oct. 2000.

How is transmucosal drug delivery different from conventional drug delivery?

This approach utilizes the oral mucosa as a means of introducing systemic agents, 1 and can be distinguished from mucosal drug delivery, as the latter aims to deliver drugs locally, rather than systemically. 1 Transmucosal delivery offers several advantages over conventional oral drug delivery.

Where does a transmucosal drug enter the body?

transmucosal [trans′mu-ko′sal] entering through, or across, a mucous membrane, as the administration of a drug via the cavity between the cheek and gum.